With the prevalence of several microbial and cancerous disease humans are always at verge of finding safe and plant based remedies as compared to conventional synthetic ones. For this purpose numerous plants, microbial and marine source shave been investigated by the scientists all over the world.
Currently the priority of scientists is to discover and evolve cheaper antimicrobial, antioxidants and anticancer agents with high potential, less toxicity, fewer side effects than antibiotics and good availability.
Marine macro algae possess certain bioactive compounds1. They can produce a great diversity of secondary metabolites beneficial for human health. For this purpose researchers evaluated the biological activities of extracts from Red alga, Laurencia papillosa.
Researchers collected the red alga, L. papillosa samples from the coastal area of the Red Sea of Jeddah, Saudi Arabia. Algal extracts were prepared with dichloromethane: methanol equal ratios. Antioxidant activity, antimicrobial and anticancer assays were performed. Phytochemical analysis was also performed to detect its composition2.
A wide range of antimicrobial activity was achieved against tested pathogens with maximum inhibition activity. Algal extracts also exhibited the bactericidal effects against all tested strains. Among the algal extracts, dichloromethane: methanol (1:1) exhibited the highest antioxidant and anticancer activities. The FTIR analysis of extract revealed the presence of alcohols, phenols, ester and alkanes.
Presence of long chain unsaturated and saturated fatty acids with the dominance of palmitic acid was also detected. The pigments, protein, carbohydrates, lipid, total phenolic, flavonoid and tannin contents of alga were further assayed. Different phytochemical contents such as; phycobiliproteins, carotenoids, phenol, flavonoids, tannin, alkaloids and polyunsaturated fatty acids were also found.
It can be established that red alga possesses different biologically active compounds in it that can act as a promising antioxidant, antimicrobial, anticancer agents and may characterize in the therapeutic application & uses.
Written by: Rabeeia
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17 November, 2019