A study was conducted by a group of researchers in order to justify the folkloric use of Trilepisium madagascariense, for treating gastrointestinal infections in Nigeria. They investigated the antimicrobial activities and determine the pharmacologically bioactive compounds present in this plant to justify its traditional folkloric use in treating diarrhoea1.
Medicinal plants have certain pharmacological and therapeutic values which are of great importance in the pharmaceutical world2. Almost 75% of pharmaceuticals are derived from bioactive compounds present in traditional medicinal plants3. This has led the increasing demand in scientific exploration and justification of many herbal plants used in folk medicine with no scientific proof.
Trilepisium madagascariense is a medicinal plant which is also known as false-fig or urn-fig tree. It grows extensively in the tropical and subtropical West and Central Africa and other also. Traditionally the stem bark of this plant has been sued to treat various ailments like; arthritis, rheumatism, diarrhea and dysentery while the roots are used against parasitic infections.
The leaves of T. madagascariense have proved to exhibit antidiabetic and anti-hyperglycemic activities4. In order to justify all these properties scientifically this study was conducted. The pharmacologically bioactive compounds in the ethanol stem back extract of false fig were determined using chromatography and spectrometry while its antimicrobial activities were assayed in vitro by agar well diffusion.
The spectra identified many compounds and acids having therapeutic potentials such as; Betulin, Paromomycin, 1-4-Hydroxylysine lactone etc. antibacterial activity was also found. The presence of paromomycin with antidiarrhoeal activity in the extract justifies the use of this plant in the folkloric treatment of gastrointestinal infections. This plant is, therefore, a significant source for isolating novel drugs having significant therapeutic potentials.
Written by: Rabeeia
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17 November, 2019