Due to enhancing focus towards natural products for preventing various diseases, scientists are hunting more natural plants having healthy benefits. In this regard, the genus Momordica is important which consists of about 825 species of annual as well perennial plants that are distributed in East Africa, Caribbean and Southern America1. Leaves, roots as well as fruits of these plant species are utilized to make traditional medicinal because of presence of phytoconstituents.
Momordica boivinii is one of the species of genus Momordica and carry many useful properties. According to Choi and team, the stems and leaves of this plant are used to treat stomach problem2. Moreover, another astonishing aspect of this species is that its aqueous extract exhibits anti-HIV activity3. Additionally, its leaf and fruit are also utilized to cure pneumonia in Ethopia4.
List of this plant regarding treatment of different ailments is so long as its fresh roots as well leaves are also found to be effectual to treat gonorrhea and intestinal parasites5. Furthermore, by mixing its leaves with vegetables form an effective appetite stimulant as well. Fruit juice of M. boivinii in combination with Allium sativum (Garlic) are also being employed to prevent health issues such as diabetes, diarrhoea, skin problem, hypertension, menstrual problems, abdominal pain, intestinal pain, abortion, breast cancer as well as anthrax. However, chemical constituents of this species have not been investigated yet.
Therefore, these useful aspects urged Filippo Tamiru, Legesse Adane and Banchiwosen Bekele6 to perform phytochemical screening tests on extracts of the root of this plant species as well as to isolate compounds from these extracts. For this procedure, scientists extracted the root material of M. boivinii by using 4 solvent systems including n-hexane, dichloromethane, dichloromethane/methanol (50:50% by volume) and methanol by means of maceration technique as well as sequential extraction approach. Then, these extracts were subjected to phytochemical screening tests. Afterwards, these researchers subjected the dichloromethane/methanol (50:50% by volume) extract to column chromatographic separation.
The outcomes of this investigation confirmed the effectiveness and use of this plant species in traditional medicine. But, scientists recommended the biological activity test to obtain complete knowledge regarding its efficacy as source of current drugs. Conclusively, this study will assist to improve the secondary metabolites further in future with their medical point of view.
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17 November, 2019