Rabbit is a valuable creature and because of their low cholesterol and fat contents as well as elevated levels of essential amino-acid1, commercial production of rabbits as a source of protein has been increased. Moreover, this is also preferred for models to perform medical research. But unfortunately, rabbits are facing serious consequences of coccidiosis; a disease that causes digestive disorders in rabbits2
It is caused because of intracellular protozoon parasites particularly where sanitation is poor and leads to major deaths in domestic rabbits. Its signs and symptoms include weight loss, mild intermittent to severe diarrhea with faeces containing mucus or blood and results in dehydration, decreased rabbit breeding3.
Two types of coccidiosis are reported in rabbits; intestinal as well as hepatic. This diseases is considered as the most costly and prevalent infectious disease in commercial rabbit systems. Conventional anti-coccidial drugs possess toxic effects as well as produce resistance in parasites. Therefore, due to occurrence of drug resistance constraints4, residual hazardous impacts of drugs in meat of animals and experts are shifting towards substitutes to manage these parasitic issuses5.
In this regard, Psidium guajava has gained attention. It is a medicinal plant and it is reported that its leaf extract possess a broad spectrum of biological activities including anticough, antibacterial, haemostasis6, antidiarrhoeal narcotic7 as well as antioxidant charateristics8. Hence, Yamssi Cedric9 and team designed a research to investigate the anticoccidial and antioxidant activities of crude extracts of P. guajava.
In this experiment, scientists employed the sporulation inhibition bioassay to examine the activity of Psidium guajava extracts on sporulation of Eimeria flavescens, Eimeria stiedae, Eimeria intestinalis and Eimeria magna oocysts as well as sporozoites. Moreover, this set up was checked aftervery 24 and 48 hours for the oocysticidal activities and after 12 and 24 hours to check anti-sporozoidal activities. Afterwards, final data was determined through one-way analysis of variance (ANOVA) as well as Waller-Duncan test via SPSS.
The outcomes of this study confirmed the application of P. guajava against coccidiosis by Agricultural farmers in Cameroon. But, more detailed research is needed to discover the effectiveness of this plant as anticoccidials, antioxidants as well its mode of action. Conclusively, these findings will aid to reveal the critical areas of coccidiosis and oxidative stress in future.
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18 August, 2019