Nonalcoholic fatty liver disease (NAFLD) is caused when lipids get accumulated abnormally in hepatocytes1. As the name mentions that it’s the disorder of the liver and is known as the main cause of chronic liver ailments. However, it can be recovered to some extent and don’t progress further if the fundamental cause is removed. It is reported that NAFLD is caused directly because of some factors including inactive lifestyle and amplified use of high-fat foods as well as carbonated drinks having elevated amounts of fructose2.
To date, there exists no effective treatment of this disorder despite its prevalence. Currently, scientists have found that nutrients can play a significant role in this regard. These nutrients can be either in the form of dietary supplements or functional foods. Dietary supplements carry nutritional and physiological beneficial impacts. They are used to supplement the basic diet with necessary nutrients that are deficient in the regular diet3.
A dietary supplement can be a plant or part of a plant and possess antioxidants. Moreover, they have various phyto-chemical components with several chemical characteristics. They can be used potentially against many diseases. Moreover, they are environment friendly and good for human health.
There is no safe and confirmed therapy against fatty liver disease. However, antioxidant therapies can serve as an effective approach in this situation and can prevent fat accumulation in the liver and further damage as well4. Accordingly, scientists performed an experiment to produce a dietary supplement rich in antioxidants to prevent nonalcoholic fatty liver linked metabolic diseases and to bound its development into steatohepatitis5.
In this study, scientists used the dietary supplement having prunes, dried grapes, carrots, Cape gooseberry, pomegranate peel, chicory, sumac, sweet corn, germinated soybeans as well as vitamins B12, C and D. This investigation was performed on thirty male Wistar rats that were divided into 5 groups for four weeks after nonalcoholic fatty liver induction by feeding rats with high fat and cholesterol diet5.
This study revealed that the tested formula, with its powerful antioxidant and anti-inflammatory properties was found to be a potential agent for preventing metabolic disorders in affected rats. These results support the application of the tested dietary supplement as an effective therapy to improve nonalcoholic fatty liver disease (NAFLD) and to prevent the progression inflammatory steatohepatitis.
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